ANTIOXIDANT ACTIVITY OF 5-(SUBSTITUTED BENZYLIDENE) THIAZOLIDINEDIONE DERIVATIVES
نویسندگان
چکیده
منابع مشابه
Synthesis and Antimicrobial Evaluation of N-Substituted-5- Benzylidene-2,4-Thiazolidinedione Derivatives
A series of N-substituted-2,4-thiazolidinedione derivatives (TZDs) were prepared via N-alkylation of 2,4-TZD at position 3 using substituted benzyl halides. Synthesized N-substituted-2,4-TZD was then substituted at position 5 with substituted aromatic aldehyde according to Knoevenagel condensation method. Structures of the compounds were elucidated using various spectral techniques viz. I...
متن کاملSynthesis and Antimicrobial Evaluation of N-Substituted-5- Benzylidene-2,4-Thiazolidinedione Derivatives
A series of N-substituted-2,4-thiazolidinedione derivatives (TZDs) were prepared via N-alkylation of 2,4-TZD at position 3 using substituted benzyl halides. Synthesized N-substituted-2,4-TZD was then substituted at position 5 with substituted aromatic aldehyde according to Knoevenagel condensation method. Structures of the compounds were elucidated using various spectral techniques viz. IR, 1HN...
متن کاملsynthesis and antimicrobial evaluation of n-substituted-5- benzylidene-2,4-thiazolidinedione derivatives
a series of n-substituted-2,4-thiazolidinedione derivatives (tzds) were prepared via n-alkylation of 2,4-tzd at position 3 using substituted benzyl halides. synthesized n-substituted-2,4-tzd was then substituted at position 5 with substituted aromatic aldehyde according to knoevenagel condensation method. structures of the compounds were elucidated using various spectral techniques viz. ir, 1hn...
متن کاملSynthesis of 3- Benzylidene, 5-Substituted 3-Benzylidene, 3- Hetarylmethylene and 5-Substituted Hetarylmethylene Derivatives of In- dolin-2-ones
A wide variety of titled compounds, several of which have neuro-protecting properties has been prepared in yields ranging between 70 to 90%. The compounds were identified by 1 HNMR, 13 C NMR, 1D and 2D NOE analysis, and HRMS. An investigation of the effect of certain 5-substitutuents on the E to Z ratios in DMSO-d6 was carried out. The 5nitro and 5-acetyl substituents were not isomerized, where...
متن کامل5-benzylidenerhodanine and 5-benzylidene-2-4-thiazolidinedione based antibacterials.
Herein we outline the antibacterial activity of amino acid containing thiazolidinediones and rhodanines against Gram-positive bacteria Staphylococcus aureus ATCC 31890, Staphylococcus epidermidis and Bacillus subtilis ATCC 6633. The rhodanine derivatives were generally more active than the analogous thiazolidinediones. Compounds of series 5 showed some selectivity for Bacillus subtilis ATCC 663...
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ژورنال
عنوان ژورنال: World Journal of Pharmaceutical Research
سال: 2017
ISSN: 2277-7105
DOI: 10.20959/wjpr20179-9276